Postdoctoral opening at the University of Illinois at Chicago

Postdoctoral or visiting scientist position is available in the laboratory of Dr. Marina Guizzetti, Associate Professor in the Department of Psychiatry at the University of Illinois at Chicago/Jesse Brown VA medical center, Chicago, USA.  The main research interest in the laboratory is the identification of novel mechanisms of astrocyte-neuron interactions involved in neuronal structural plasticity. In particular, we are investigating mechanisms of neurite outgrowth/dendritic arborization modulated by extracellular matrix proteins and extracellular matrix protease systems released by astrocytes and their alterations following ethanol exposure and brain injury.  Heavy prenatal alcohol exposure is associated with learning and behavioral abnormalities, as seen in Fetal Alcohol Spectrum Disorders (FASD); cognitive impairments are also observed in individuals who abuse alcohol. Furthermore, we are interested in characterizing the epigenetic mechanisms involved in the effects of ethanol on astrocytes leading to alteration in astrocyte secreted proteins. We use or plan to use pharmacological, biochemical, genetic, and behavioral tools both in vivo and in vitro to address these questions.The ideal candidate for the position is a highly motivated individual who has a recent PhD, extensive scientific and technical background in molecular and cellular neurobiology, excellent oral and written communication skills in English, an interactive personality, and a strong work ethic.Experience in epigenetic research (DNA methylation and histone modification), animal behavior, cell culture, and/or lipid research (cholesterol, phospholipids, and lipoprotein determinations) are a plus. Applications should be sent to Dr. Marina Guizzetti via e-mail at marinag@uic.edu and should include: Curriculum Vitae; a statement of research interests; the names and addresses (including e-mail addresses and phone numbers) of three scholars who are willing to serve as references for the applicant.Preferred starting date: April-May, 2014.